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Based on mass balance studies, the systemic availability of taro-etodolac from the tablet is at least 80 .

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Within one hour of ingestion of a potentially toxic amountactivated charcoal should be consideredAlternativelyin adultsgastric lavage should be considered within one hour of indigestion of a potentially life-threatening overdose.

In limited studies so far availableNSAIDs can appear in breast milk in very low concentrationsNSAIDs shouldif possiblebe avoided when breastfeeding.

The risk of GI bleedingulceration or perforation is higher with increasing NSAID dosesin patients with a history of ulcerparticularly if complicated with haemorrhage or perforationsee section 4.3and in the elderlyThese patients should commence treatment on the lowest dose availableCombination therapy with protective agentse.gmisoprostol or proton pump inhibitorsshould be considered for these patientsand also for patients requiring concomitant low dose aspirinor other drugs likely to increase gastrointestinal risksee below and section 4.5)

Taking etodolac and warfarin together may increase your risk of stomach bleeding.

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