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Hypersensitivity reactionsincluding anaphylaxisangioedemarashand urticariaerythema multiformearthralgiamyalgiaelevated creatine phosphokinasemyopathy/rhabdomyolysissee WARNINGS AND PRECAUTIONSelevations in liver transaminaseshepatitisabdominal painthrombocytopeniapancreatitisnauseadizzinessparesthesiadepressionheadachecholelithiasischolecystitis.

If you also take cholestyraminecolestipolor colesevelamWait at least 4 hours after taking any of these medicines before you take ezetimibeYou may also take ezetimibe 2 hours before taking any of these other medicines.

You may need frequent blood tests to check your liver function if you take ezetimibe with a statin medicine.

In this limited controlled studythere was no significant effect on growth or sexual maturation in the adolescent boys or girlsor on menstrual cycle length in girls.

No evidence of mutagenicity was observed in vitro in a microbial mutagenicityAmestest with Salmonella typhimurium and Escherichia coli with or without metabolic activationNo evidence of clastogenicity was observed in vitro in a chromosomal aberration assay in human peripheral blood lymphocytes with or without metabolic activationIn additionthere was no evidence of genotoxicity in the in vivo mouse micronucleus test.

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the most commonly reported adverse reactions incidence 2 and greater than statin alone in the zetia statin controlled clinical trial database of 11,308 patients were nasopharyngitis 3.

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